membrane-associated ATPase, may provide energy for DNA transport
function
genetic competence
product
ATP-binding protein
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue][SW|Categories] containing this gene/protein
[SW|genetic competence], [SW|membrane proteins], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|ComK regulon]Gene
Phenotypes of a mutant
knockout has 1000-fold reduction in transformability compared to the wild-type [Pubmed|8412657]The protein
Protein family
helicase family (according to Swiss-Prot)Modification
phosphorylated on Arg-20, Arg-186, and Arg-446 [Pubmed|22517742][SW|Localization]
cell membrane [Pubmed|7984101]localizes to cell poles in competent cells [Pubmed|16009133]localizes to cell poles [Pubmed|21278288][SW|Interactions]
[SW|ComGA]-[SW|ComFA] [Pubmed|17630974][SW|ComEC]-[SW|ComFA] [Pubmed|17630974][protein|search|CoiA]-[SW|ComFA] [Pubmed|17630974][protein|search|SsbB]-[SW|ComFA] [Pubmed|17630974][protein|search|DprA]-[SW|ComFA] [Pubmed|17630974][protein|search|RecA]-[SW|ComFA] [Pubmed|17630974]Expression and Regulation
Operon
''[SW|comFA]-[SW|comFB]-[SW|comFC]-[protein|search|yvyF]-[protein|search|flgM]-[protein|search|flgN]-[protein|search|flgK]-[protein|search|flgL]'' [Pubmed|8412657][SW|Sigma factor]
''[SW|comFA]'': [protein|search|SigA] [Pubmed|8412657]Regulatory mechanism
[protein|search|ComK]: transcription activation [Pubmed|8412657]References
Reviews
Original publications
11814663,8412657,7984101,16009133,8045895,17630974,21278288,22517742,21397556 
