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ugd [Mon Aug 31 2015 13:57:11 GMT+0200 (CEST)]
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ugd [Mon Aug 31 2015 13:57:11 GMT+0200 (CEST)]

UDP-glucose dehydrogenase
locus
BSU36230
pI
5.03
mw
47.00 kDa
function
unknown
product
UDP-glucose dehydrogenase
essential
no
ec
1.1.1.22
synonyms
ywqF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.7|Phosphorylation on a Tyr residue]
    • syns
    ywqF

    [SW|Categories] containing this gene/protein

  • [SW|phosphoproteins], [SW|sporulation proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|DegU regulon], [SW|Spo0A regulon]

    • The protein

    Catalyzed reaction/ biological activity

  • UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH (according to Swiss-Prot)

    • Protein family

  • UDP-glucose/GDP-mannose dehydrogenase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|TuaD], [protein|search|YtcA]

    • Modification

  • phosphorylation on Tyr-70 by [protein|search|PtkA] [Pubmed|12970183], dephosphorylated by [protein|search|PtpZ] [Pubmed|15866923]

    • Effectors of protein activity

  • phosphorylation by [protein|search|PtkA] stimulates activity of Ugd [Pubmed|15741737]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''[protein|search|tkmA]-[protein|search|ptkA]-[protein|search|ptpZ]-[protein|search|ugd]'' [Pubmed|20815827,12970183]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|20815827]

    • Regulatory mechanism

  • [SW|Spo0A]: transcription activation [Pubmed|26283769]
  • [protein|search|DegU]-P: transcription activation [Pubmed|26283769]
  • [protein|search|AbrB]: transcription repression [Pubmed|20817675]

    • References

  • 12970183,19258708,15741737,15866923,20815827,24728941,26283769