rplA [Fri Jan 29 2016 16:44:44 GMT+0100 (CET)]

ribosomal protein

locus: BSU01030

pI: 9.00

mw: 24.00 kDa

function: translation

product: ribosomal protein L1 (BL1)

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|universally conserved proteins]

This gene is a member of the following [SW|regulons]

• [SW|stringent response]

Gene

Coordinates on the chromosome (coding sequence): 119,111 -> 119,809

The protein

Protein family

• ribosomal protein L1P family (according to Swiss-Prot)

Structure

• [PDB|3J9W] (the [SW|ribosome])

[SW|Interactions]

• [protein|search|YsxC]-[protein|search|RplA] [Pubmed|17981968]
• [protein|search|RplA]-[protein|search|CshA] [Pubmed|23175651]

Expression and Regulation

Regulation

• [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
• expression transiently increases in the forespore [Pubmed|22848659]

Biological materials

two-hybrid system

• B. pertussis adenylate cyclase-based bacterial two hybrid system ([SW|BACTH]), available in [SW|Jörg Stülke]'s lab

FLAG-tag construct

• GP1094 (erm, based on [SW|pGP1087]), available in [SW|Jörg Stülke]'s lab

References

• 17981968,19653700,11463749,22848659,23175651,23002217