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yxdM [2017-8-11 16:0:3]
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yxdM [2017-8-11 16:0:3]

ABC transporter (permease)
locus
BSU39630
pI
9.27
mw
70.35 kDa
protein length
622 aa Sequence Blast
gene length
1866 bp Sequence Blast
function
export of toxic peptides
product
ABC transporter (permease)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.3|Export of peptides]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    4,068,550 → 4,070,418

    The protein

    Protein family

  • ABC-4 integral membrane protein family (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|8B4267532B9788AEB5EF39E2695C1FDA494C7055|yxdL]-[gene|4423383A3F6DAFDFA210F4BEEF7D8CBEC674DCEA|yxdM]-[gene|6D9153BA698101C3EE1CD68B76419ECD300740F8|yxeA]
    description
    [Pubmed|15289557]

    regulatory mechanism

  • [protein|F3C5505E311E6DDABAFA87899F28CF6596CDBA63|YxdJ]: activation, [Pubmed|15289557], in [regulon|F3C5505E311E6DDABAFA87899F28CF6596CDBA63|YxdJ regulon]

    • regulation

  • induced by a cationic antimicrobial peptide, LL-37 ([protein|search|YxdJ]) [Pubmed| 21078927]
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    Biological materials

    Mutant

  • MGNA-B705 (yxdM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1704 NBRP B. subtilis, Japan]

    • References

  • 10092453,15289557,21283517