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truB [2020-05-04 17:59:31]
tRNA pseudouridine 5S synthase
function
tRNA modification
product
tRNA pseudouridine 5S synthase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]Gene
Coordinates
1,736,886 1,737,815
The protein
Catalyzed reaction/ biological activity
uridine55 in tRNA --> pseudouridine55 in tRNA (according to UniProt)Protein family
pseudouridine synthase TruB family (single member, according to UniProt)Structure
[PDB|1ZE1] (from Thermotoga maritima, 36% identity) [pubmed|14990747]Biological materials
Mutant
BKE16660 ([gene|425FC9847D10A6FA9725D6523CD3213C57B371BE|truB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCCTTTCACTCCTTC, downstream forward: _UP4_CAATAGAAAAAAGGTGACCGBKK16660 ([gene|425FC9847D10A6FA9725D6523CD3213C57B371BE|truB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCCTTTCACTCCTTC, downstream forward: _UP4_CAATAGAAAAAAGGTGACCGReferences
24371284,7489483,14990747