SubtiBank SubtiBank
yitJ [2017-8-11 16:0:3]
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yitJ [2017-8-11 16:0:3]

methionine synthase
locus
BSU11010
pI
5.34
mw
67.75 kDa
protein length
612 aa Sequence Blast
gene length
1836 bp Sequence Blast
function
methionine biosynthesis
product
methionine synthase
essential
no
ec
2.1.1.13
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.11|Biosynthesis/ acquisition of methionine/ S-adenosylmethionine/ based on similarity]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,178,757 → 1,180,595

    The protein

    [SW|Localization]

  • membrane associated [Pubmed|18763711]

    • Expression and Regulation

    Operons

    genes
    [gene|41AB43191DDB2E0698D92FFD1ECEF45100F1F3F0|yitJ]

    description

  • [Pubmed|10094622]

    • regulatory mechanism

  • [regulon|S-box|S-box]: termination/antitermination, [pubmed|10094622], in [regulon|S-box|S-box]

    • regulation

  • induced by methionine starvation ([SW|S-box]) [Pubmed|10094622]
  • the [SW|S-box] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B195 (yitJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1194 NBRP B. subtilis, Japan]

    • References

    The [protein|search|S-box]

  • 19258532,10094622,18039762,20951706,22543867

    • Other publications

  • 19779461,12107147,18763711,22960854