SubtiBank SubtiBank
pyrH [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]
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pyrH [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

uridylate kinase
locus
BSU16510
pI
5.10
mw
25.00 kDa
function
pyrimidine biosynthesis
product
uridylate kinase
essential
no
ec
2.7.4.22
synonyms
smbA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.4|Biosynthesis/ acquisition of pyrimidine nucleotides]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
    • syns
    smbA

    [SW|Categories] containing this gene/protein

  • [SW|biosynthesis/ acquisition of nucleotides]

    • This gene is a member of the following [SW|regulons]

  • [SW|stringent response]

    • The protein

    Catalyzed reaction/ biological activity

  • ATP + UMP = ADP + UDP (according to Swiss-Prot)

    • Protein family

  • UMP kinase family (according to Swiss-Prot)

    • Structure

  • [PDB|2JJX] (from ''Bacillus anthracis'', 42% identity, 64% similarity) [Pubmed|18625239]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Regulation

  • [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]

    • References

  • 12869195,8206849,1709162