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pyrH [Mon Aug 31 2015 13:54:21 GMT+0200 (CEST)]
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pyrH [Mon Aug 31 2015 13:54:21 GMT+0200 (CEST)]

uridylate kinase
Locus
BSU16510
Isoelectric point
5.00
Molecular weight
25.00 kDa
Function
pyrimidine biosynthesis
Product
uridylate kinase
Essential
no
E.C.
2.7.4.22
Synonyms
smbA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Nucleotide metabolism → Biosynthesis/ acquisition of nucleotides → Biosynthesis/ acquisition of pyrimidine nucleotides
  • Groups of genes → Essential genes

    • Categories containing this gene/protein

  • biosynthesis/ acquisition of nucleotides

    • This gene is a member of the following regulons

  • stringent response

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,719,802 -> 1,720,524

    The protein

    Catalyzed reaction/ biological activity

  • ATP UMP = ADP UDP (according to Swiss-Prot)

    • Protein family

  • UMP kinase family (according to Swiss-Prot)

    • Structure

  • 2JJX (from Bacillus anthracis, 42% identity, 64% similarity) PubMed

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Regulation

  • RelA dependent downregulation (Class I) during stringent response PubMed

    • References

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