SubtiBank SubtiBank
ctc [Tue Dec 13 2016 11:16:29 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ctc [Tue Dec 13 2016 11:16:29 GMT+0100 (CET)]

general stress protein, similar to ribosomal protein L25
locus
BSU00520
pI
4.00
mw
21.00 kDa
function
unknown
product
ribosomal protein
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]

    • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|general stress proteins (controlled by SigB)]

    • This gene is a member of the following [SW|regulons]

  • [SW|SigB regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    58,783 -> 59,397

    The protein

    Protein family

  • Ctc subfamily (according to Swiss-Prot)

    • Structure

  • [PDB|1FEU] (from ''Thermus thermophilus'', 32% identity, 53% similarity) [Pubmed|11418764]

    • [SW|Localization]

  • in the ribosome (large subunit) [Pubmed|12432960]

    • [SW|Interactions]

  • [SW|5S rRNA]-[protein|search|Ctc] [Pubmed|12432960]

    • Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation [PubMed|17981983]

    • Expression and Regulation

    Operon

  • ''[protein|search|gcaD]-[protein|search|prs]-[protein|search|ctc]'' [Pubmed|8522540]
  • ''[protein|search|ctc]'' [Pubmed|6790515]

    • [SW|Sigma factor]

  • ''[protein|search|gcaD]'': [protein|search|SigA] [Pubmed|8522540]
  • ''[protein|search|ctc]'': [protein|search|SigB] [Pubmed|6790515]

    • Regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528]

    • Regulatory mechanism

  • alternative [SW|sigma factor], [protein|search|SigB] [Pubmed|6790515]

    • Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation [PubMed|17981983]

    • Biological materials

    Mutant

  • GP500(spc), available in [SW|Jörg Stülke]'s lab [Pubmed|12432960]
  • CS206 (''[protein|search|ctc]''::''aphA3'', available in [SW|Colin Harwood]'s and [SW|Jörg Stülke]'s labs) [Pubmed|27197833]

    • Expression vector

  • expression/ purification with N-terminal His-tag in ''E. coli'': pGP804 (in [SW|pWH844]), available in [SW|Jörg Stülke]'s lab [Pubmed|12432960]

    • Antibody

  • available in [SW|Jörg Stülke]'s lab [Pubmed|12432960]

    • References

    Reviews

  • 19216708

    • Original publications

  • 2836704,3123466,3100810,8522540,15805528,12432960,6790515,2836704,116131,11418764,23002217,27197833