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yukC [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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yukC [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

membrane pseudokinase-like protein, part of the type VII protein secretion system YukD-YukC-YukB-YueB-YueC
locus
BSU31890
pI
4.68
mw
51.00 kDa
function
export of YukE
product
membrane pseudokinase-like protein, part of the type VII protein secretion system
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|protein secretion], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|DegU regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,274,462 -> 3,275,817

    Phenotypes of a mutant

  • loss of secretion of [protein|search|YukE] [Pubmed|24798022]
  • The protein

    [SW|Localization]

  • membrane (according to SwissProt) [Pubmed|23861817]
  • Expression and Regulation

    Operon

  • ''[protein|search|yukE]-[protein|search|yukD]-[protein|search|yukC]-[protein|search|yukB]-[protein|search|yueB]-[protein|search|yueC]'' [Pubmed|22383849,15576783]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|22383849]
  • Regulation

  • not expressed in the lab strain 168, due to lack of [protein|search|DegU]-P [Pubmed|23861817]
  • expressed in the stationary phase [Pubmed|23861817]
  • Regulatory mechanism

  • [protein|search|DegU]-P: transcription activation [Pubmed|23861817]
  • References

    Reviews

  • 19155186,11973144
  • Original publications

  • 15576783,22383849,23861817,24798022