sdpI [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

immunity protein, protection against SdpC

Locus: BSU33780

Isoelectric point: 9.61

Molecular weight: 23.00 kDa

Function: protection against SdpC

Product: immunity protein

Essential: no

Synonyms: yvaZ

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Coping with stress → Toxins, antitoxins and immunity against toxins
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• toxins, antitoxins and immunity against toxins, membrane proteins

This gene is a member of the following regulons

• AbrB regulon, SdpR regulon

Gene

Coordinates on the chromosome (coding sequence): 3,466,434 -> 3,467,057

The protein

Paralogous protein(s)

• YfhL, YbgB

Effectors of protein activity

• in the presence of extracellular SdpC, SdpI binds and sequesters SdpR , this results in induction of the sdpR-sdpI operon PubMed

Localization

• membrane (according to Swiss-Prot)

Interactions

• SdpI-SdpR PubMed

Expression and Regulation

Operon

• sdpR-sdpI PubMed

Sigma factor

• SigA PubMed

Regulation

• repressed during logrithmic growth (AbrB) PubMed
• induced by extracellular SdpC (SdpR) PubMed

Regulatory mechanism

• AbrB: transcription repression PubMed
• SdpR: transcription repression PubMed

References

Reviews

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Original Publications

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