sdpI

immunity protein, protection against SdpC

Locus: BSU_33780

Isoelectric point: 9.61

Molecular weight: 23.15 kDa

Protein length: 207 aa

Gene length: 624 bp

Function: protection against SdpC

Product: immunity protein

Essential: no

Synonyms: yvaZ

Genomic Context

Loading

Categories containing this gene/protein

• Lifestyles → Coping with stress → Toxins, antitoxins and immunity against toxins
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,466,434 3,467,057

The protein

Paralogous protein(s)

• YfhL, YbgB

Effectors of protein activity

• in the presence of extracellular SdpC, SdpI binds and sequesters SdpR , this results in induction of the sdpR-sdpI operon PubMed

Localization

• membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: sdpR-sdpI
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
  • SdpR: repression, PubMed, in SdpR regulon

  Regulation

  • induced by extracellular SdpC (SdpR) PubMed

Biological materials

Mutant

• MGNA-A454 (yvaZ::erm), available at the NBRP B. subtilis, Japan
• BKE33780 (sdpI::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AATTATGGAAATTATATTTT, downstream forward: _UP4_TGAAAAAGTGTCTTGCGGAG
• BKK33780 (sdpI::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AATTATGGAAATTATATTTT, downstream forward: _UP4_TGAAAAAGTGTCTTGCGGAG

References

Reviews

Loading

Original Publications

Loading