choline ABC transporter (ATP-binding protein)
function
compatible solute transport
product
choline ABC transporter (ATP-binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.4|Uptake of compatible solutes for osmoprotection][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|coping with hyper-osmotic stress], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|GbsR regulon], [SW|OpcR regulon], [SW|RemA regulon]Gene
Coordinates on the chromosome (coding sequence)
3,462,105 -> 3,463,250
The protein
Protein family
[SW|ABC transporter] family (according to Swiss-Prot)Paralogous protein(s)
[SW|OpuCA][SW|Domains]
2 [SW|CBS domain]s (256-314, 316-374)[SW|Localization]
associated to the membrane (via [SW|OpuBB]-[SW|OpuBD]) [Pubmed|10092453][SW|Interactions]
[SW|OpuBA]-([SW|OpuBB]-[SW|OpuBD])-[SW|OpuBC] [Pubmed|10092453]Expression and Regulation
Operon
''[SW|opuBA]-[SW|opuBB]-[SW|opuBC]-[SW|opuBD]'' [Pubmed|10216873][SW|Sigma factor]
[protein|search|SigA] [Pubmed|10216873]Regulation
induced by salt stress [Pubmed|10216873]induced by choline ([protein|search|GbsR]) [Pubmed|22408163]Regulatory mechanism
[protein|search|GbsR]: transcription repression [Pubmed|22408163][protein|search|OpcR]: transcription repression [Pubmed|23960087][protein|search|RemA]: transcription activation [Pubmed|23646920]Biological materials
Expression vector
pGP2938 (N-terminal His-tag, purification from ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s labReferences
10092453,9925583,10216873,21296969,23960087,22408163,23646920 
