yfmI

similar to macrolide-efflux transporter

Locus: BSU_07460

Isoelectric point: 10.00

Molecular weight: 45.45 kDa

Protein length: 406 aa

Gene length: 1221 bp

Function: unknown

Product: unknown

Essential: no

Synonyms

Genomic Context

Loading

Categories containing this gene/protein

• Cellular processes → Transporters → Transporters/ other → Other transporters
• Lifestyles → Coping with stress → Resistance against toxins/ antibiotics/ based on similarity
• Groups of genes → Membrane proteins

Gene

Coordinates: 819,311 820,531

The protein

Protein family

• major facilitator superfamily (according to UniProt)

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: yfmI-yfmJ
  Description: PubMed

  Regulatory mechanism

  • Spo0A: activation, PubMed, in Spo0A regulon
  • AbrB: repression, PubMed, in AbrB regulon

  Regulation

  • expressed under conditions that trigger sporulation (Spo0A) PubMed

  Additional information

  • A ncRNA is predicted between 'YfmI' and 'YfmG' PubMed

Biological materials

Mutant

• MGNA-C242 (yfmI::erm), available at the NBRP B. subtilis, Japan
• BKE07460 (yfmI::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGTATCCTCCCTTGGA, downstream forward: _UP4_TAATAAATATATAAAATTTA
• BKK07460 (yfmI::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGTATCCTCCCTTGGA, downstream forward: _UP4_TAATAAATATATAAAATTTA
• GP2580 (yfmI::tet comIQ12L) (in DK1042) available in Jörg Stülke's lab

References

Loading