RNA polymerase sigma factor SigI
function
control of a class of heat shock genes
product
RNA polymerase sigma factor SigI
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.4|Heat shock proteins][SW|Categories] containing this gene/protein
[SW|transcription], [SW|sigma factors and their control], [SW|heat shock proteins]This gene is a member of the following [SW|regulons]
[SW|SigI regulon], [SW|WalR regulon]Gene
Coordinates on the chromosome (coding sequence)
1,411,892 -> 1,412,647
Phenotypes of a mutant
temperature-sensitive growth on agar plates [Pubmed|11157964]The protein
[SW|Interactions]
[protein|search|RsgI]-[protein|search|SigI], the interaction inhibits SigI activity [Pubmed|17185538][protein|search|SigI]-[protein|search|RpoB]-[protein|search|RpoC]Additional information
overexpression of SigI suppresses ''[protein|search|mreB] [SW|mreBH] [protein|search|mbl]'' mutants [Pubmed|19114499]Expression and Regulation
Operon
''[protein|search|sigI]-[protein|search|rsgI]'' [Pubmed|17185538][SW|Sigma factor]
[protein|search|SigI] [Pubmed|17185538]Regulation
induced at high temperature ([protein|search|SigI], [protein|search|WalR]) [Pubmed|24125693,23199363,17185538]Regulatory mechanism
[protein|search|WalR]: transcription activation [Pubmed|24125693,23199363]References
19114499,17185538,11157964,18156261,21541672,24125693,23199363,26744224 
