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polA [2017-8-11 16:0:3]
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polA [2017-8-11 16:0:3]

DNA polymerase I, required for repair of UV- or MMS-induced DNA damage
Locus
BSU29090
Isoelectric point
4.92
Molecular weight
98.89 kDa
Protein length
880 aa Sequence Blast
Gene length
2640 bp Sequence Blast
Function
DNA replication
Product
DNA polymerase I
Essential
no
E.C.
2.7.7.7
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
2,973,182 → 2,975,824

Phenotypes of a mutant

  • strongly reduced stationary phase mutagenesis PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • has DNA polymerase and 5'-3' exonuclease activity, but no 3'-5' exonuclease activity PubMed
  • Protein family

  • DNA polymerase type-A family (according to Swiss-Prot)
  • Paralogous protein(s)

  • ExoR, one of the two proteins has to be present for viability PubMed
  • Structure

  • 1XWL (large fragment, corresponds to AA 310 to 880, Geobacillus stearothermophilus)
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon
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    References

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