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defA [Mon Aug 31 2015 13:54:15 GMT+0200 (CEST)]
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defA [Mon Aug 31 2015 13:54:15 GMT+0200 (CEST)]

formylmethionine deformylase
Locus
BSU15720
Isoelectric point
4.00
Molecular weight
17.00 kDa
Function
translation
Product
formylmethionine deformylase
Essential
no
E.C.
3.5.1.88
Synonyms
yloK, def
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Translation → Translation/ other
  • Information processing → Protein synthesis, modification and degradation → Protein modification → Protein maturation

    • Categories containing this gene/protein

  • translation, protein modification

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,646,512 -> 1,646,994

    The protein

    Catalyzed reaction/ biological activity

  • Formyl-L-methionyl peptide H2O = formate methionyl peptide (according to Swiss-Prot)

    • Protein family

  • polypeptide deformylase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • DefB

    • Interactions

  • DefA-RplV PubMed
  • Map competes with peptide deformylase (DefA), the first enzyme to act on nascent chains, for binding sites at the ribosomal tunnel exit PubMed

    • Expression and Regulation

    Operon

  • defA-fmt-yloM PubMed

    • Sigma factor

  • SigA defA-fmt-yloM PubMed

    • References

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