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sigE [2017-05-09 15:36:34]
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sigE [2017-05-09 15:36:34]

RNA polymerase sporulation mother cell-specific (early) sigma factor SigE
locus
BSU15320
pI
9.21
mw
27.55 kDa
protein length
239 aa Sequence Blast
gene length
717 bp Sequence Blast
function
transcription of sporulation genes (early mother cell)
product
RNA polymerase sporulation mother cell-specific (early) sigma factor SigE
essential
no
synonyms
spoIIGB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]
  • [category|SW 6|Groups of genes] → [category|SW 6.11|Efp-dependent proteins]

    • Gene

    Coordinates
    1,604,771 → 1,605,490

    The protein

    Catalyzed reaction/ biological activity

  • [SW|RNA polymerase] [SW|sigma factor], active in the mother cell

    • Protein family

  • sigma-70 factor family (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|221829E084DA78ACE1C2DFCEB6E59EDA534FF55D|spoIIGA]-[gene|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]-[gene|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]
    description
    [Pubmed|1902213]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|2512576], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG]: sigma factor, [Pubmed|1902213], in [regulon|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG regulon]
  • [protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF]: sigma factor, in [regulon|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF regulon]

    • regulatory mechanism

  • [protein|5A6FBAE6553343092862CB79E150F934978C32A9|SinR]: repression, in [regulon|5A6FBAE6553343092862CB79E150F934978C32A9|SinR regulon]
  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: activation, [PubMed|8288522,15687200], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • ''[SW|spoIIGA]'': expressed under conditions that trigger sporulation ([SW|Spo0A]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]

    • additional information

  • the mRNA half-life is about 2.6 min [PubMed|24163345]
    • view in new tab

    Labs working on this gene/protein

  • [SW|Bill Haldenwang], San Antonio, USA
  • [SW|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]

    • References

    Reviews

  • 20833318

    • The [SW|SigE regulon]

  • 12662922,15383836,14523133

    • Original Publications

  • 7768847,8002606,8449878,10438769,9922240,10869437,13129963,7585939,1729246,9244279,11849534,8231808,8171000,15547282,15882622,9537362,1542693,1946462,8550479,10498732,15978076,9006059,2115864,7473719,12644503,2115871,15028683,7601832,9150232,1624450,1744037,1400231,2495274,11886548,2514119,1744038,14523132,18436644,8288522,15687200,25835496,23169620,21362630,20802044,21478340