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sigE [Mon Aug 31 2015 13:54:11 GMT+0200 (CEST)]
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sigE [Mon Aug 31 2015 13:54:11 GMT+0200 (CEST)]

RNA polymerase sporulation mother cell-specific (early) sigma factor SigE
locus
BSU15320
pI
9.21
mw
27.00 kDa
function
transcription of sporulation genes (early mother cell)
product
RNA polymerase sporulation mother cell-specific
(early) sigma factor SigE
essential
no
synonyms
spoIIGB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]
  • [category|SW 6|Groups of genes] → [category|SW 6.11|Efp-dependent proteins]
    • syns
    spoIIGB

    [SW|Categories] containing this gene/protein

  • [SW|transcription], [SW|sigma factors and their control], [SW|sporulation proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|SinR regulon], [SW|Spo0A regulon], [SW|Efp-dependent proteins]

    • The protein

    Catalyzed reaction/ biological activity

  • [SW|RNA polymerase] [SW|sigma factor], active in the mother cell

    • Protein family

  • sigma-70 factor family (according to Swiss-Prot)

    • [SW|Interactions]

  • [protein|search|SigE]-([protein|search|RpoB]-[protein|search|RpoC])
  • [SW|SpoIIGA]-[protein|search|SigE] (Processing) [Pubmed|21362630]
  • [protein|search|CsfB]-[protein|search|SigE] to inhibit [protein|search|SigE] activity [Pubmed|25835496]

    • Expression and Regulation

    Operon

  • ''[SW|spoIIGA]-[protein|search|sigE]-[protein|search|sigG]'' [Pubmed|1902213]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|2512576]

    • Regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]

    • Regulatory mechanism

  • repression by [protein|search|SinR]
  • [SW|Spo0A]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]

    • Labs working on this gene/protein

  • [SW|Bill Haldenwang], San Antonio, USA
  • [SW|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]

    • References

    Reviews

  • 20833318

    • The [SW|SigE regulon]

  • 12662922,15383836,14523133

    • Original Publications

  • 7768847,8002606,8449878,10438769,9922240,10869437,13129963,7585939,1729246,9244279,11849534,8231808,8171000,15547282,15882622,9537362,1542693,1946462,8550479,10498732,15978076,9006059,2115864,7473719,12644503,2115871,15028683,7601832,9150232,1624450,1744037,1400231,2495274,11886548,2514119,1744038,14523132,18436644,8288522,15687200,25835496,23169620,21362630,20802044,21478340