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mntA [2017-10-19 17:42:15]
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mntA [2017-10-19 17:42:15]

manganese ABC transporter (binding protein, lipoprotein)
Locus
BSU30770
Isoelectric point
6.16
Molecular weight
33.26 kDa
Protein length
306 aa Sequence Blast
Gene length
918 bp Sequence Blast
Function
manganese uptake
Product
manganese ABC transporter (binding protein)
Essential
no
Synonyms
ytgA

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,145,038 → 3,145,958

Phenotypes of a mutant

  • essential according to Kobayashi et al., but a mutant has been constructed and studied by Que and Helmann, 2000
  • The protein

    Protein family

  • bacterial solute-binding protein 9 family (according to Swiss-Prot)
  • Paralogous protein(s)

    Localization

  • cell membrane (according to Swiss-Prot), extracellular lipoprotein (signal peptide) PubMed
  • Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • MntR: repression, PubMed, in MntR regulon
  • Regulation

  • repressed at high Mn(II) concentrations (MntR) PubMed
  • Additional information

  • A ncRNA is predicted between 'mntA' and 'menC' PubMed
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    Biological materials

    Mutant

  • MGNA-A285 (ytgA::erm), available at the NBRP B. subtilis, Japan
  • BKE30770 (ΔmntA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTTCTCCTCCTCTTTG, downstream forward: _UP4_TAAAGAAAAGAGGTGGAGGA
  • BKK30770 (ΔmntA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTTCTCCTCCTCTTTG, downstream forward: _UP4_TAAAGAAAAGAGGTGGAGGA
  • Labs working on this gene/protein

  • John Helmann, Cornell University, USA Homepage
  • References

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