SubtiBank SubtiBank
murC
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murC

UDP-N-acetylmuramoyl-L-alanine synthetase
Locus
BSU_29790
Isoelectric point
5.31
Molecular weight
48.20 kDa
Protein length
432 aa Sequence Blast
Gene length
1299 bp Sequence Blast
Function
peptidoglycan precursor biosynthesis
Product
UDP-N-acetylmuramoyl-L-alanine synthetase
Essential
yes
E.C.
6.3.2.8
Synonyms
ytxF

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,048,177 3,049,475

Phenotypes of a mutant

  • essential PubMed
  • murC is dispensable in wall-less L-forms PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • ATP + L-alanine + UDP-N-acetyl-α-D-muramate --> ADP + H+ + phosphate + UDP-N-acetyl-α-D-muramoyl-L-alanine (according to UniProt)
  • Protein family

  • MurCDEF family (according to UniProt)
  • Structure

  • 1GQQ (from Haemophilus influenzae, 31% identity)
  • Localization

  • cytoplasm (Homogeneous) PubMed
  • forms banded patterns along the length of the cell, this pattern formation depends on MreB PubMed
  • Expression and Regulation

    Operons

    References

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