efeU [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

elemental iron uptake system (permease), high affinity uptake of ferric iron (Fe(III))

locus: BSU38280

pI: 8.00

mw: 52.00 kDa

function: elemental iron uptake

product: elemental iron uptake system (permease)

essential: no

synonyms: ywbL

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.2|Elemental iron transport system]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.5|Elemental iron transport system]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|Fur regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,929,105 -> 3,930,550

The protein

[SW|Localization]

• cell membrane (according to Swiss-Prot)

[SW|Interactions]

• [protein|search|EfeO]-[protein|search|EfeU]-[protein|search|EfeB] [Pubmed|23180473,23764491]

Expression and Regulation

Operon

• ''[protein|search|efeU]-[protein|search|efeO]-[protein|search|efeB]'' [Pubmed|9353933]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|23764491]

Regulation

• induced upon iron starvation ([protein|search|Fur]) [Pubmed|12354229]

Regulatory mechanism

• [protein|search|Fur]: transcription repression [Pubmed|12354229]

References

• 16672620,23180473,12354229,23764491,27795321