L-ribulose-phosphate 4-epimerase
function
arabinose utilization
product
L-ribulose-phosphate 4-epimerase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.6|Utilization of arabinan/ arabinose/ arabitol][SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources]This gene is a member of the following [SW|regulons]
[SW|AraR regulon], [SW|CcpA regulon]The protein
Catalyzed reaction/ biological activity
L-ribulose 5-phosphate = D-xylulose 5-phosphate (according to Swiss-Prot)Protein family
AraD/fucA subfamily (according to Swiss-Prot)Structure
[PDB|1K0W] (from '' Escherichia coli'', 59% identity, 74% similarity) [Pubmed|11732895]Expression and Regulation
Operon
''[protein|search|araA]-[protein|search|araB]-[protein|search|araD]-[protein|search|araL]-[protein|search|araM]-[protein|search|araN]-[protein|search|araP]-[protein|search|araQ]-[protein|search|abfA]'' [Pubmed|9084180][SW|Sigma factor]
[protein|search|SigA] [Pubmed|9084180]Regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|12949161]induced by arabinose ([protein|search|AraR]) [Pubmed|10417639]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|12949161][protein|search|AraR]: transcription repression [Pubmed|10417639]References
2500424,9084180,10417639,12949161,9084180 
