ycbF [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

glucarate dehydratase

locus: BSU02490

pI: 5.59

mw: 50.00 kDa

function: glucarate utilization

product: glucarate dehydratase

essential: no

ec: 4.2.1.40

synonyms: gudD

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.14|Utilization of glucarate/galactarate]

[SW|Categories] containing this gene/protein

• [SW|utilization of specific carbon sources]

This gene is a member of the following [SW|regulons]

• [SW|YcbG regulon]

Gene

Coordinates on the chromosome (coding sequence): 271,800 -> 273,167

The protein

Catalyzed reaction/ biological activity

• d-glucarate = 5-dehydro-4-deoxy-D-glucarate + H₂O (according to Swiss-Prot)

Protein family

• GlucD subfamily (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|ycbC]-[protein|search|ycbD]-[protein|search|ycbE]-[protein|search|ycbF]-[protein|search|ycbG]-[protein|search|ycbH]-[protein|search|ycbJ]'' [Pubmed|12044674]

Regulation

• induced by D-glucarate/galactarate ([protein|search|YcbG]) [Pubmed|12044674]

Regulatory mechanism

• [protein|search|YcbG]: transcription repression [Pubmed|12044674]

References

• 12044674