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galK [Thu Aug 18 2016 16:39:49 GMT+0200 (CEST)]
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galK [Thu Aug 18 2016 16:39:49 GMT+0200 (CEST)]

galactokinase
locus
BSU38200
pI
5.00
mw
43.00 kDa
function
galactose utilization
product
galactokinase
essential
no
ec
2.7.1.6
synonyms
ipa-35d

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.8|Utilization of galactose]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources]
  • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,920,638 -> 3,921,810

    The protein

    Catalyzed reaction/ biological activity

  • ATP D-galactose = ADP alpha-D-galactose 1-phosphate (according to Swiss-Prot)
  • Protein family

  • GalK subfamily (according to Swiss-Prot)
  • Structure

  • [PDB|1PIE] (from ''Lactococcus lactis'', 43% identity, 60% similarity) [Pubmed|12796487]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|galK]-[protein|search|galT]'' [Pubmed|9353933]
  • ''[protein|search|ywcC]-[protein|search|gtaC]-[protein|search|galK]-[protein|search|galT]'' [Pubmed|22383849,22893383]
  • Regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
  • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|10666464]
  • References

  • 9353933,10666464,22383849,22893383