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galK
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galK

galactokinase
Locus
BSU_38200
Isoelectric point
5.15
Molecular weight
43.36 kDa
Protein length
390 aa Sequence Blast
Gene length
1173 bp Sequence Blast
Function
galactose utilization
Product
galactokinase
Essential
no
E.C.
2.7.1.6
Synonyms
ipa-35d
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of galactose

    • Gene

    Coordinates
    3,920,638 3,921,810

    The protein

    Catalyzed reaction/ biological activity

  • α-D-galactose + ATP --> ADP + α-D-galactose 1-phosphate + H+ (according to UniProt)

    • Protein family

  • GHMP kinase family (together with IspE and ThrB) (according to UniProt)

    • Structure

  • 1PIE (from Lactococcus lactis, 43% identity, 60% similarity) PubMed

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    galK-galT
    Description
    PubMed

    Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon

    • Regulation

  • repressed by glucose (CcpA) PubMed
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    Genes
    ywcC-gtcA-galK-galT
    Description
    PubMed

    Regulation

  • repressed by glucose (CcpA) PubMed
    • view in new tab

    Biological materials

    Mutant

  • BKE38200 (galK::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTGCAATCACCTTTCTG, downstream forward: _UP4_AGAGAACTAAAGGGGGAGTG
  • BKK38200 (galK::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTGCAATCACCTTTCTG, downstream forward: _UP4_AGAGAACTAAAGGGGGAGTG

    • References

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