comEC [Mon Jun 20 2016 20:54:53 GMT+0200 (CEST)]

channel protein for DNA binding and uptake

locus: BSU25570

pI: 6.00

mw: 86.00 kDa

function: genetic competence

product: DNA channel

essential: no

synonyms: comD

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
• [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|genetic competence], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|ComK regulon], [SW|ComN regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,637,543 -> 2,639,873

The protein

[SW|Localization]

• cell membrane [Pubmed|15661011]
• localizes to one or both cell poles [Pubmed|21278288]

[SW|Interactions]

• [SW|ComEC]-[SW|ComEA] [Pubmed|17630974]
• [SW|ComEC]-[SW|ComFA] [Pubmed|17630974]
• [SW|ComEC]-[SW|ComGA] [Pubmed|17630974]

Expression and Regulation

Operon

• ''[SW|comEA]-[SW|comEB]-[SW|comEC]'' [Pubmed|7968523,19028902]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|7968523]

Regulatory mechanism

• post-translational control by [protein|search|ComN] [Pubmed|19028902]
• ''[protein|search|yutB]'' is required for transcription [Pubmed|19028902]
• [protein|search|ComK]: transcription activation [Pubmed|8196543]

References

Reviews

• 15083159

Original publications

• 17630974,11814663,15661011,7968523,21278288,19028902