rtpA

anti-TRAP

Locus: BSU_02530

Isoelectric point: 4.86

Molecular weight: 5.51 kDa

Protein length: 53 aa

Gene length: 162 bp

Function: regulation of tryptophan biosynthesis

Product: anti-TRAP

Essential: no

Synonyms: yczA

Genomic Context

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Categories containing this gene/protein

• Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of aromatic amino acids
• Information processing → Regulation of gene expression → Transcription factors and their control → Control of transcription factor (other than two-component system)

Gene

Coordinates: 277,160 277,321

The protein

Structure

• 1N53 (structure of T box RNA), 2BX9, 2ZP9 (complex with MtrB)

Localization

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: rtpA-ycbK
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • T-box: transcription termination/ antitermination, MtrB PubMed, in T-box

  Regulation

  • rtpA: induced by tryptophan limitation (T-box in the mRNA leader) PubMed

Biological materials

Mutant

• BKE02530 (rtpA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTGATATCCTCCTTTCT, downstream forward: _UP4_TAAAGGAGAAAAGCTGAGCT
• BKK02530 (rtpA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTGATATCCTCCTTTCT, downstream forward: _UP4_TAAAGGAGAAAAGCTGAGCT

References

Reviews

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Original Publications

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