adhA [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

thiol-dependent aldehyde dehydrogenase, repair of damaged thiol-containing proteins

locus: BSU27010

pI: 5.37

mw: 37.00 kDa

function: response to toxic formaldehyde

product: thiol-dependent aldehyde dehydrogenase,
reduction of aldehydes

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[SW|Categories] containing this gene/protein

• [SW|resistance against oxidative and electrophile stress]

This gene is a member of the following [SW|regulons]

• [SW|AdhR regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,756,312 -> 2,757,361

Expression and Regulation

Operon

• ''[protein|search|adhA]-[protein|search|yraA]'' [Pubmed|19170879]

Regulation

• induced in the presence of the toxic carbonyls methylglyoxal and formaldehyde ([protein|search|AdhR]) [Pubmed|19170879]

Regulatory mechanism

• [protein|search|AdhR]: transcription activation [Pubmed|19170879]

References

• 19170879