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bltD [2019-08-07 13:59:39]
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bltD [2019-08-07 13:59:39]

spermidine/ spermine acetyltransferase
Locus
BSU_26600
Isoelectric point
6.09
Molecular weight
17.70 kDa
Protein length
152 aa Sequence Blast
Gene length
459 bp Sequence Blast
Function
spermidine degradation
Product
spermidine/ spermine acetyltransferase
Essential
no
E.C.
2.3.1.57
Synonyms
bmr2D,bmtD

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
2,718,344 2,718,802

The protein

Catalyzed reaction/ biological activity

  • Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine (according to Swiss-Prot)
  • Structure

  • 2FL4 (from Enterococcus faecalis, 45% identity)
  • Expression and Regulation

    Operons

    Genes
    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • BltR: activation, PubMed, in BltR regulon
  • Mta: activation, PubMed, in Mta regulon
  • Regulation

  • induced in the presence of polyamines PubMed
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    Biological materials

    Mutant

  • MGNA-C455 (bltD::erm), available at the NBRP B. subtilis, Japan
  • BKE26600 (bltD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACTACATTCTCCTTTTT, downstream forward: _UP4_TAGATATCCAAGCCTCCTTG
  • BKK26600 (bltD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACTACATTCTCCTTTTT, downstream forward: _UP4_TAGATATCCAAGCCTCCTTG
  • References

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