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pucK [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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pucK [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

uric acid permease
locus
BSU32440
pI
8.35
mw
44.00 kDa
function
purine utilization
product
uric acid permease
essential
no
synonyms
yunK

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.6|Nucleotide/ nucleoside transporter]
  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|utilization of nucleotides], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|PucR regulon], [SW|TnrA regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,331,857 -> 3,333,149

    The protein

    Protein family

  • xanthine/uracil permease family (according to Swiss-Prot)
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|pucR]-[protein|search|pucJ]-[protein|search|pucK]-[protein|search|pucL]-[protein|search|pucM]'' [Pubmed|12823818]
  • ''[protein|search|pucJ]-[protein|search|pucK]-[protein|search|pucL]-[protein|search|pucM]'' [Pubmed|12029039]
  • [SW|Sigma factor]

  • ''[protein|search|pucJ]'': [protein|search|SigA] [Pubmed|12029039]
  • Regulation

  • expressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|12823818]
  • induced in the presence of purine nucleotides (inducer: allantoin) ([protein|search|PucR]) [Pubmed|12029039]
  • Regulatory mechanism

  • [protein|search|TnrA]: transcription activation [Pubmed|12823818]
  • [protein|search|PucR]: transcription activation [Pubmed|12029039]
  • References

  • 11344136,25755103,12823818,12029039