SubtiBank SubtiBank
tsaD [2017-09-25 17:24:17]
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tsaD [2017-09-25 17:24:17]

required for threonyl carbamoyl adenosine (t6A) modification of tRNAs that pair with ANN codons in mRNA (together with TsaC), universally conserved protein
Locus
BSU05940
Isoelectric point
5.02
Molecular weight
36.69 kDa
Protein length
346 aa Sequence Blast
Gene length
1038 bp Sequence Blast
Function
tRNA modification
Product
tRNA modification enzyme
Essential
yes
E.C.
2.3.1.234
Synonyms
ydiE,gcp
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Translation → tRNA modification and maturation
  • Groups of genes → Essential genes
  • Groups of genes → Universally conserved proteins

    • Gene

    Coordinates
    643,258 → 644,298

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs using L-threonylcarbamoyl-AMP (TsaB-TsaD-TsaE) PubMed

    • Modification

  • in vitro phosphorylated by TsaE PubMed

    • Structure

  • 3ZET (from Salmonella typhimurium, 46% identity) PubMed

    • Additional information

  • universally conserved protein

    • Expression and Regulation

    Operons

    Genes
    thiL-tsaE-tsaB-ydiD-tsaD
    Description
    PubMed
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    References

    Publications on the corresponding protein from other species

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