function
mother cell metabolism
product
methylisocitrate lyase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.9|Utilization of branched-chain amino acids][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|sporulation proteins], [SW|membrane proteins], [SW|poorly characterized/ putative enzymes]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|SigE regulon]Gene
Coordinates on the chromosome (coding sequence)
2,507,298 -> 2,508,203
The protein
Catalyzed reaction/ biological activity
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate (according to Swiss-Prot)Protein family
Methylisocitrate lyase family (according to Swiss-Prot)Structure
[PDB|1MUM] (enzyme of ''E. coli''), [PDB|3KZ2] (the enzyme from ''B. anthracis'')[SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|mmgA]-[protein|search|mmgB]-[protein|search|mmgC]-[protein|search|mmgD]-[protein|search|mmgE]-[protein|search|yqiQ]'' [Pubmed|8759838][SW|Sigma factor]
[protein|search|SigE] [Pubmed|15699190,8759838]Regulation
expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,8759838]repressed by glucose ([protein|search|CcpA]) [Pubmed|8759838]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|8759838]References
12706720,8759838,15699190 
