gutB [Mon Aug 31 2015 13:52:51 GMT+0200 (CEST)]

D-sorbitol dehydrogenase

locus: BSU06150

pI: 5.21

mw: 38.00 kDa

function: glucitol utilization

product: D-sorbitol dehydrogenase

essential: no

ec: 1.1.1.14

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.11|Utilization of glucitol]

[SW|Categories] containing this gene/protein

• [SW|utilization of specific carbon sources]

This gene is a member of the following [SW|regulons]

• [SW|GutR regulon]

The protein

Catalyzed reaction/ biological activity

• L-iditol + NAD⁺ = L-sorbose + NADH (according to Swiss-Prot)

Protein family

• zinc-containing alcohol dehydrogenase family (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|gutB]-[protein|search|gutP]'' [Pubmed|12897001]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|8195086]

Regulation

• induced by glucitol ([protein|search|GutR]) [Pubmed|8195086]

Regulatory mechanism

• [protein|search|GutR]: transcriptional activation [Pubmed|8195086]

References

• 1460002,12897001,8195086