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ndoA [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]
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ndoA [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

RNase EndoA, MazF family toxin, UACAU-specific mRNA interferase
Locus
BSU04660
Isoelectric point
4.89
Molecular weight
12.00 kDa
Function
unknown
Product
mRNA interferase
Essential
no
Synonyms
ydcE, mazF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → RNA synthesis and degradation → RNases → Endoribonucleases
  • Lifestyles → Coping with stress → Toxins, antitoxins and immunity against toxins
  • Lifestyles → Coping with stress → Toxins, antitoxins and immunity against toxins → Type 2 TA systems
    • Syns
    ydcE, mazF

    Categories containing this gene/protein

  • RNAses, toxins, antitoxins and immunity against toxins

    • The protein

    Catalyzed reaction/ biological activity

  • specifically cleaves a five-base sequence, UACAU PubMed

    • Protein family

  • pemK family (according to Swiss-Prot)

    • Effectors of protein activity

  • the activity is inhibited by the interaction with NdoAI PubMed

    • Structure

  • 1NE8 PubMed
  • 4MDX (NdoA-RNA) PubMed
  • 4ME7 (NdoA-NdoAI complex) PubMed

    • Interactions

  • NdoA(2)-NdoAI(2)-NdoA(2) PubMed
  • the active protein forms dimers PubMed

    • Expression and Regulation

    Operon

  • ndoAI-ndoA PubMed

    • References

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