SubtiBank SubtiBank
dtrR
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dtrR

D-Tyr resistance regulator (MarR family)
Locus
BSU_38450
Isoelectric point
8.76
Molecular weight
19.50 kDa
Protein length
171 aa Sequence Blast
Gene length
516 bp Sequence Blast
Function
resistance to D-Tyr
Product
transcription factor (MarR family)
Essential
no
Synonyms
ywaE,ipa-10r
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other

    • Gene

    Coordinates
    3,946,394 3,946,909

    The protein

    Catalyzed reaction/ biological activity

  • repression of the dtrR-tyrZ operon PubMed

    • Protein family

  • MarR family

    • Domains

  • HTH marR-type domain (aa 33-166) (according to UniProt)

    • Structure

  • 3CDH (from Silicibacter pomeroyi, 24% identity)

    • Expression and Regulation

    Operons

    Genes
    dtrR-tyrZ
    Description
    PubMed

    Sigma factors

  • TyrZ: sigma factor, PubMed, in TyrZ regulon

    • Regulatory mechanism

  • DtrR: repression, PubMed, in DtrR regulon
  • T-box: anti-termination, in T-box

    • Regulation

  • induced by tyrosine limitation (T-box) PubMed
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    Biological materials

    Mutant

  • MGNA-B219 (ywaE::erm), available at the NBRP B. subtilis, Japan
  • BKE38450 (dtrR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTTTAGGCCTGCCTTA, downstream forward: _UP4_GCTGACAATCTTCATACAAC
  • BKK38450 (dtrR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTTTAGGCCTGCCTTA, downstream forward: _UP4_GCTGACAATCTTCATACAAC

    • References

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