SubtiBank SubtiBank
ylaG
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ylaG

similar to GTP-binding elongation factor
locus
BSU_14770
pI
4.97
mw
68.21 kDa
protein length
612 aa Sequence Blast
gene length
1839 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
bipA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.11|Translation factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.5|Cold stress proteins]

    • Gene

    Coordinates
    1,546,121 1,547,959

    The protein

    Catalyzed reaction/ biological activity

  • in E. coli, the corresponding protein (BipA) incorporates ribosomal protein [protein|20485A785D3AF82889F2018D3EA5B5FA33E64E95|L6] into the nascent large ribosomal subunit [pubmed|30305394]

    • Protein family

  • [SW|TRAFAC class translation factor GTPase superfamily] (according to UniProt)
  • [SW|Classic translation factor GTPase family] (according to UniProt)

    • [SW|Domains]

  • [SW|tr-type G domain] (aa 5-200) (according to UniProt)

    • Structure

  • [PDB|4ZCM] (from E. coli, 55% identity) [pubmed|26163516]

    • [SW|Localization]

  • cytoplasm (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]-[gene|8DE3D48909BDBD2091432047E79063E9EEE63115|ylaH]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]
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    Biological materials

    Mutant

  • MGNA-A536 (ylaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/536 NBRP B. subtilis, Japan]
  • BKE14770 ([gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTTTTCATCTCCTAAAA, downstream forward: _UP4_TAATCTCGTGCAGAATTTGA
  • BKK14770 ([gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTTTTCATCTCCTAAAA, downstream forward: _UP4_TAATCTCGTGCAGAATTTGA

    • References

  • 11948165,12399512,30305394,26163516