yfkJ [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

general stress protein, protein tyrosine phosphatase, required for protection against paraquat stress

locus: BSU07880

pI: 4.56

mw: 17.00 kDa

function: survival of stress conditions

product: protein tyrosine phosphatase

essential: no

ec: 3.1.3.48

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[SW|Categories] containing this gene/protein

• [SW|protein modification], [SW|general stress proteins (controlled by SigB)], [SW|resistance against oxidative and electrophile stress]

This gene is a member of the following [SW|regulons]

• [SW|SigB regulon]

Gene

Coordinates on the chromosome (coding sequence): 862,004 -> 862,474

The protein

Catalyzed reaction/ biological activity

• Protein tyrosine phosphate + H₂O = protein tyrosine + phosphate (according to Swiss-Prot)

Protein family

• low molecular weight phosphotyrosine [SW|protein phosphatase] family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|YwlE]

Structure

• [PDB|4ETM]

Expression and Regulation

Operon

• ''[protein|search|yfkJ]-[protein|search|yfkI]-[protein|search|yfkH]'' (according to [http://dbtbs.hgc.jp/COG/prom/yfkJIH.html DBTBS])

[SW|Sigma factor]

• SigA [Pubmed|11532142], [protein|search|SigB] [Pubmed|15805528,11532142]

Regulation

• induced by stress ([protein|search|SigB]) [Pubmed|15805528,11532142]

References

• 15866923,15995210,22582280,15805528,11532142