product
ribosomal protein L14
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue][category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins][SW|Categories] containing this gene/protein
[SW|translation], [SW|essential genes], [SW|universally conserved proteins], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|stringent response]Gene
Coordinates on the chromosome (coding sequence)
140,451 -> 140,819
Phenotypes of a mutant
essential [Pubmed|23002217,12682299]The protein
Protein family
[SW|ribosomal protein] L14P family (according to Swiss-Prot)Modification
phosphorylated on Arg-7 [Pubmed|22517742]Structure
[PDB|1WHI] (Geobacillus stearothermophilus)[PDB|3J9W] (the [SW|ribosome]) [Pubmed|25903689][SW|Interactions]
[protein|search|RplN]-[protein|search|YqeL] [Pubmed|22829778], the interaction serves to silence [SW|translation] [Pubmed|22829778]Expression and Regulation
Operon
''[protein|search|rpsJ]-[protein|search|rplC]-[protein|search|rplD]-[protein|search|rplW]-[protein|search|rplB]-[protein|search|rpsS]-[protein|search|rplV]-[protein|search|rpsC]-[protein|search|rplP]-[protein|search|rpmC]-[protein|search|rpsQ]-[protein|search|rplN]-[protein|search|rplX]-[protein|search|rplE]-[protein|search|rpsN]-[protein|search|rpsH]-[protein|search|rplF]-[protein|search|rplR]-[protein|search|rpsE]-[protein|search|rpmD]-[protein|search|rplO]'' [Pubmed|9371452][SW|Sigma factor]
[protein|search|SigA] two promoters, about 140bp and 200bp upstream of the start codon [Pubmed|9371452]Regulation
[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]strongly repressed in response to glucose starvation in M9 medium [Pubmed|23033921]References
8635744,19653700,9371452,11948165,22517742,22829778,23033921,23002217,25903689 
