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abfA [Mon Aug 31 2015 13:56:09 GMT+0200 (CEST)]
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abfA [Mon Aug 31 2015 13:56:09 GMT+0200 (CEST)]

alpha-L-arabinofuranosidase
locus
BSU28720
pI
5.34
mw
56.00 kDa
function
arabinan degradation
product
alpha-L-arabinofuranosidase
essential
no
ec
3.2.1.55
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.6|Utilization of arabinan/ arabinose/ arabitol]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources]
  • This gene is a member of the following [SW|regulons]

  • [SW|AraR regulon], [SW|CcpA regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides (according to Swiss-Prot)
  • Protein family

  • glycosyl hydrolase 51 family (according to Swiss-Prot)
  • Structure

  • [PDB|1QW8] (complex with Ara-alpha-Xyl, Geobacillus stearothermophilus), [PDB|1PZ3] (Geobacillus stearothermophilus)
  • [SW|Localization]

  • forms hexamers [Pubmed|23797805]
  • Expression and Regulation

    Operon

  • ''[protein|search|araA]-[protein|search|araB]-[protein|search|araD]-[protein|search|araL]-[protein|search|araM]-[protein|search|araN]-[protein|search|araP]-[protein|search|araQ]-[protein|search|abfA]'' [Pubmed|9084180]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9084180]
  • Regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|12949161]
  • induced by arabinose ([protein|search|AraR]) [Pubmed|10417639]
  • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|12949161]
  • [protein|search|AraR]: transcription repression [Pubmed|10417639]
  • References

  • 14973026,9084180,18757805,10417639,12949161,9084180,23797805