dnaB [Mon Aug 31 2015 13:56:10 GMT+0200 (CEST)]

initiation of chromosome replication/ membrane attachment protein, part of the replisome

locus: BSU28990

pI: 5.00

mw: 54.00 kDa

function: DNA replication

product: initiation of chromosome replication/ membrane attachment protein

essential: yes

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|DNA replication], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence): 2,964,148 -> 2,965,566

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

[SW|Localization]

• Membrane-proximal (Spotty) [Pubmed|16479537]
• forms foci, close to oriC [Pubmed|10844689]

[SW|Interactions]

• [protein|search|DnaB]-[protein|search|PriA] [Pubmed|11585815]
• [protein|search|DnaB]-[protein|search|DnaI] [Pubmed|11842108]
• [protein|search|DnaB]-[protein|search|DnaC] [Pubmed|11250911]
• [protein|search|DnaD]-[protein|search|DnaB] [Pubmed|15186423,19707554]
• [protein|search|DnaB]-[protein|search|DnaX] [Pubmed|14757052]
• part of the [SW|replisome]: [protein|search|PolC]-[protein|search|HolA]-[protein|search|HolB]-[protein|search|DnaX]-[protein|search|DnaN]-[protein|search|DnaG]-[protein|search|DnaC]-[protein|search|DnaI]-[protein|search|DnaD]-[protein|search|SsbA]-[protein|search|DnaE]-[protein|search|PriA]-[protein|search|DnaB] [Pubmed|20122408]
• part of the [SW|primosome]: [protein|search|DnaA]-[protein|search|DnaG]-[protein|search|DnaC]-[protein|search|DnaI]-[protein|search|DnaD]-[protein|search|DnaB] [Pubmed|22797751]

References

Reviews

• 22797751

Original publications

• 19707554,15686560,12718886,2554322,11250911,15186423,11842108,11585815,16479537,19415803,14757052,10844689,12974630,19968790,20071750,11679082,20122408,20199598,20587500,21097613