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mlpA [2018-10-30 12:52:51]
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mlpA [2018-10-30 12:52:51]

mitochondrial processing peptidase-like, involved in regulation of protease gene expression
Locus
BSU16710
Isoelectric point
5.28
Molecular weight
45.80 kDa
Protein length
409 aa Sequence Blast
Gene length
1227 bp Sequence Blast
Function
control of proteolyticc activity
Product
specific processing protease
Essential
no
Synonyms
ymxG

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,742,617 → 1,743,846

Phenotypes of a mutant

  • fivefold increased levels of proteolytic activity in their growth medium PubMed
  • The protein

    Protein family

  • peptidase M16 family (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    Biological materials

    Mutant

  • MGNA-A057 (ymxG::erm), available at the NBRP B. subtilis, Japan
  • deletion mutant, available in van Dijl lab
  • BKE16710 (ΔmlpA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAATTTGTTCCTCCTATTC, downstream forward: _UP4_TAAAAAGGAAAGCCTGCCCC
  • BKK16710 (ΔmlpA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAATTTGTTCCTCCTATTC, downstream forward: _UP4_TAAAAAGGAAAGCCTGCCCC
  • Labs working on this gene/protein

  • Jan Maarten van Dijl, Groningen, Netherlands
  • References

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