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cotB [Thu May 19 2016 18:56:10 GMT+0200 (CEST)]
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cotB [Thu May 19 2016 18:56:10 GMT+0200 (CEST)]

spore coat protein (outer)
locus
BSU36050
pI
9.00
mw
42.00 kDa
function
resistance of the spore
product
spore coat protein (outer)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.5|Class V]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]

    • [SW|Categories] containing this gene/protein

  • [SW|sporulation proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|GerE regulon], [SW|GerR regulon], [SW|SigK regulon], [SW|SigE regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    3,714,739 -> 3,715,881

    The protein

    Modification

  • phosphorylated on serine residues by [SW|CotH] [Pubmed|27185916]
  • maturation of CotB requires [SW|CotG] [Pubmed|26953338]

    • [SW|Localization]

  • outer spore coat, at the middle of the spore as a ring- or spiral-like structure, localization depends on [protein|search|CotE] [Pubmed|22171814,19933362]

    • [SW|Interactions]

  • [protein|search|CotB]-[protein|search|CotG] [Pubmed|14762006]
  • [protein|search|CotB]-[protein|search|CotH] [Pubmed|27185916]

    • Expression and Regulation

    Operon

  • ''[protein|search|cotH]-[protein|search|cotB]-[protein|search|ywrJ]'' [Pubmed|22383849]
  • ''[protein|search|cotB]-[protein|search|ywrJ]'' [Pubmed|22383849]

    • [SW|Sigma factor]

  • [protein|search|SigE] [Pubmed|15383836], [protein|search|SigK] [Pubmed|15699190,1691789],

    • Regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE], [protein|search|GerR]) [Pubmed|15699190,1691789,15383836,20435725]

    • Regulatory mechanism

  • [protein|search|GerE]: transcription activation [Pubmed|1518043]
  • [protein|search|GerR]: transcription activation [Pubmed|20435725]

    • Biological materials

    Mutant

  • 1S102 ( ''cotB''::''cat''), [Pubmed|2821284], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S102&Search=1S102 BGSC]

    • References

  • 22171814,19933362,1518043,2821284,14762006,1691789,19933362,15699190,20435725,15383836,25259857,26953338,27185916