sporulation initiation phosphotransferase of the phosphorelay
function
initiation of sporulation
product
sporulation initiation phosphotransferase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.3|The phosphotransferases][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.3|The phosphotransferases][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue][SW|Categories] containing this gene/protein
[SW|phosphorelay], [SW|phosphoproteins]Gene
Coordinates on the chromosome (coding sequence)
2,853,981 -> 2,854,559
Phenotypes of a mutant
Arrest of sporulation at stage 0 (initiation) [http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=4633157 PubMed]The protein
Structure
[PDB|1F51] (complex with [SW|Spo0F]), [PDB|1IXM][SW|Interactions]
[SW|Spo0B]-[SW|Spo0F][SW|Spo0B]-[SW|Spo0A][protein|search|YmcA]-[SW|Spo0F] [Pubmed|23490197]Expression and Regulation
Operon
''[SW|spo0B]-[protein|search|obg]-[protein|search|yszB]-[protein|search|pheA]'' [Pubmed|22383849][SW|Sigma factor]
[protein|search|SigA] [Pubmed|2537815]Biological materials
Mutant
[http://www.ncbi.nlm.nih.gov/nuccore/254763670 spo0B12], point mutation 85C>T (=R29W), available in [http://www.bgsc.org/ BGSC] 1S54[http://www.ncbi.nlm.nih.gov/nuccore/254763672 spo0B136], amber mutation 103A>T (=K35X), available in [http://www.bgsc.org/ BGSC] 1S16[http://www.ncbi.nlm.nih.gov/nuccore/254763674 spo0B580ts], point mutation 193G>A (=E65K), available in [http://www.bgsc.org/ BGSC] 1S90[http://www.ncbi.nlm.nih.gov/nuccore/254763676 spo0B581ts], point mutation 461G>A (=G154D), available in [http://www.bgsc.org/ BGSC] 1S91References
20413551,12730135,2437099,9141138,3918016,9299348,16788205,12067336,9726997,2118512,10997904,1846779,9477965,2537815,23490197 
