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sdpR [2017-12-15 18:20:47]
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sdpR [2017-12-15 18:20:47]

transcriptional repressor (ArsR family) of the sdpR-sdpI operon
locus
BSU33790
pI
7.33
mw
10.10 kDa
protein length
90 aa Sequence Blast
gene length
270 bp Sequence Blast
function
regulation of protection against SdpC
product
transcriptional regulator (ArsR family)
essential
no
synonyms
yvbA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins]

    • Gene

    Coordinates
    3,467,054 → 3,467,326

    The protein

    Protein family

  • [SW|ArsR family]

    • Effectors of protein activity

  • [protein|3FB5839A7A80CF52E627FF1744E50490F5CC390F|SdpI] binds and sequesters [protein|29A3EC8FB0C763A973273AA14EAEB904847C3002|SdpR] if extracellular [protein|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|SdpC] is present, this results in induction of the ''[gene|29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR]-[gene|3FB5839A7A80CF52E627FF1744E50490F5CC390F|sdpI]'' operon [Pubmed|16469701]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR]-[gene|3FB5839A7A80CF52E627FF1744E50490F5CC390F|sdpI]
    description
    [Pubmed|12817086]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|16469701], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|16469701], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]
  • [protein|29A3EC8FB0C763A973273AA14EAEB904847C3002|SdpR]: repression, [Pubmed|16469701], in [regulon|29A3EC8FB0C763A973273AA14EAEB904847C3002|SdpR regulon]

    • regulation

  • induced by extracellular [protein|search|SdpC] ([protein|search|SdpR]) [Pubmed|16469701]
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    Biological materials

    Mutant

  • BKE33790 (Δ[gene|29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33790 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGCGTTTTCTCCTTTAC, downstream forward: _UP4_TTATGAAGAAAAATATAATT
  • BKK33790 (Δ[gene|29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33790 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGCGTTTTCTCCTTTAC, downstream forward: _UP4_TTATGAAGAAAAATATAATT

    • References

    Reviews

  • 20955377

    • Original Publications

  • 12817086,16469701,10960106