transcriptional repressor (ArsR family) of the sdpR-sdpI operon
function
regulation of protection against SdpC
product
transcriptional regulator (ArsR family)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins][SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|toxins, antitoxins and immunity against toxins]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon], [SW|SdpR regulon]The protein
Protein family
[SW|ArsR family]Effectors of protein activity
[protein|search|SdpI] binds and sequesters [protein|search|SdpR] if extracellular [protein|search|SdpC] is present, this results in induction of the ''[protein|search|sdpR]-[protein|search|sdpI]'' operon [Pubmed|16469701][SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[protein|search|SdpI]-[protein|search|SdpR] [Pubmed|16469701]Expression and Regulation
Operon
''[protein|search|sdpR]-[protein|search|sdpI]'' [Pubmed|12817086][SW|Sigma factor]
[protein|search|SigA] [Pubmed|16469701]Regulation
repressed during logrithmic growth ([protein|search|AbrB]) [Pubmed|16469701]induced by extracellular [protein|search|SdpC] ([protein|search|SdpR]) [Pubmed|16469701]Regulatory mechanism
[protein|search|AbrB]: transcription repression [Pubmed|16469701][protein|search|SdpR]: transcription repression [Pubmed|16469701]References
Reviews
Original Publications
12817086,16469701,10960106