function
major autolysin, cell separation
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.1|Autolysis][category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.5|N-acetyl-β-D-glucosaminidases][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][SW|Categories] containing this gene/protein
[SW|cell wall degradation/ turnover]This gene is a member of the following [SW|regulons]
[SW|SigD regulon]Gene
Coordinates on the chromosome (coding sequence)
3,684,826 -> 3,687,468
The protein
Catalyzed reaction/ biological activity
Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -(Man(GlcNAc)2)Asn-structure (according to Swiss-Prot)Protein family
glycosyl hydrolase 73 family (according to Swiss-Prot)[SW|Localization]
extracellular (signal peptide) [Pubmed|18957862]Expression and Regulation
Operon
''[protein|search|lytD]'' [Pubmed|7934877][SW|Sigma factor]
[protein|search|SigD] [Pubmed|7934877]Biological materials
Mutant
1A788 ( ''lytD''::''tet''), [Pubmed|7934877], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A788&Search=1A788 BGSC]1A792 ( ''lytD''::''tet''), [Pubmed|1588906], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A792&Search=1A792 BGSC]References
7934877,19542270,18957862,21821766 
