SubtiBank SubtiBank
yabJ [2017-07-26 17:40:16]
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yabJ [2017-07-26 17:40:16]

required for activity of PurR
locus
BSU00480
pI
5.13
mw
13.51 kDa
protein length
125 aa Sequence Blast
gene length
375 bp Sequence Blast
function
regulation of purine biosynthesis
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.12|Biosynthesis/ acquisition of branched-chain amino acids]
  • [category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions]

    • Gene

    Coordinates
    55,295 → 55,672

    The protein

    Protein family

  • Ref.3 (according to Swiss-Prot) YjgF family

    • Structure

  • [PDB|1QD9], 1QD9 [http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?Dopt=s&uid=11484 NCBI] [Pubmed|10557275]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|8FA635D1915108BF29A864AF4DA28ECF633F735F|ispE]-[gene|A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C|purR]-[gene|285D9E676B06119F9F4D33FC62615EC844D35BC3|yabJ]
    description
    [Pubmed|22383849]

    regulatory mechanism

  • [protein|A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C|PurR]: repression, [Pubmed|7638212], in [regulon|A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C|PurR regulon]

    • regulation

  • negative autoregulation [Pubmed|7638212]
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    Biological materials

    Mutant

  • MGNA-B911 (yabJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1910 NBRP B. subtilis, Japan]

    • References

  • 10368157,7638212,7638212,10557275