ccdA

membrane-embedded thiol-disulfide oxidoreductase

locus: BSU_17930

pI: 9.67

mw: 25.86 kDa

protein length: 235 aa

gene length: 708 bp

function: cytochrome c synthesis

product: thiol-disulfide oxidoreductase

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.4|Respiration/ other]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 1,923,234 1,923,941

The protein

Protein family

• DsbD family (single member, according to UniProt)

Structure

• [PDB|5VKV] (from Thermus thermophilus, 38% identity) [pubmed|29379172]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|27A25671205E9F6475A1EF00C72F9239AA2A767A|ccdA]-[gene|AE823A0A652509787EA032F122E59F3C3645385F|yneI]-[gene|D869177D5B1CE8B72AF89A18F03D8176ADA42664|yneJ]
  description: [Pubmed|9068642]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|10781554], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

Biological materials

Mutant

• BKE17930 ([gene|27A25671205E9F6475A1EF00C72F9239AA2A767A|ccdA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE17930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCATCATCCCTTCATG, downstream forward: _UP4_TGACGGTAAATTACTTTCGT
• BKK17930 ([gene|27A25671205E9F6475A1EF00C72F9239AA2A767A|ccdA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK17930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCATCATCCCTTCATG, downstream forward: _UP4_TGACGGTAAATTACTTTCGT

References

• 9226261,10781554,11844773,10844653,9068642,29379172