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appC [2018-05-04 13:28:44]
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appC [2018-05-04 13:28:44]

oligopeptide ABC transporter (permease)
locus
BSU11400
pI
9.78
mw
33.27 kDa
protein length
303 aa Sequence Blast
gene length
909 bp Sequence Blast
function
uptake of oligopeptides
product
oligopeptide ABC transporter (permease))
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.3|Uptake of peptides]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.4|Utilization of peptides]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,216,210 → 1,217,121

    The protein

    Protein family

  • ABC transmembrane type-1 domain (according to Swiss-Prot)

    • [SW|Localization]

  • cell membrane [Pubmed|10092453,18763711]

    • Expression and Regulation

    Operons

    genes
    [gene|325BCDCAB4003204294229B7F9F0A5F353D72B54|appD]-[gene|B88A88B4792FFFF4E1609B1FC91AAE6DBA339044|appF]-[gene|DD2C5F549759447FF1C30E5B43BCB74CE4320EF3|appA/1]-[gene|082D2012ABE3671F62211F77ED501849BF77B4EF|appA/2]-[gene|C6EB94EACDA544700A468545BD1FDA91C5FD82FB|appB]-[gene|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC]
    description
    [Pubmed|7997159]

    regulatory mechanism

  • [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]: activation, [Pubmed|25755103], in [regulon|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA regulon]
  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [pubmed|12618455] [pubmed|18083814], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]
  • [protein|F7FD94CE7AB290FBFD3A9B88F204961668F9B42C|ScoC]: repression, [Pubmed|10383984], in [regulon|F7FD94CE7AB290FBFD3A9B88F204961668F9B42C|ScoC regulon]

    • regulation

  • repressed by [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY] [Pubmed|12618455]
    • view in new tab

    Biological materials

    Mutant

  • GP2100 (D(''[gene|325BCDCAB4003204294229B7F9F0A5F353D72B54|appD]-[gene|B88A88B4792FFFF4E1609B1FC91AAE6DBA339044|appF]-[gene|082D2012ABE3671F62211F77ED501849BF77B4EF|appA/2]-[gene|C6EB94EACDA544700A468545BD1FDA91C5FD82FB|appB]-[gene|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC]'')::''spc''), available in [SW|Jörg Stülke]'s lab
  • BKE11400 (Δ[gene|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGTTTCCCTCCTTT, downstream forward: _UP4_TAAAAATGAATATCATATCT
  • BKK11400 (Δ[gene|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGTTTCCCTCCTTT, downstream forward: _UP4_TAAAAATGAATATCATATCT

    • References

  • 12618455,7997159,10092453,25755103,10383984,12618455,18763711